far too much info crammed into my head i reckon. I can tell you now that peanut allergies are one of the more serious allergies. cos they may cause systemic anaphylaxis. This can also be one of the outcomes of drug allergies, serum allergies and venom. Type I hypersensitivity. IgE is bound to surfaces of mast cells, basophils and activated eosinophils. Mast cells are activated when the IgE antibody is xlinking the FcepsilonRI on their surfaces. These mast cells then release granules of histamine, which result in the widespread dilation of blood vessels to slow down blood flow. This slow down is actually good for when leukocytes want to adhere to endothelial cells. However this decrease in blood flow also leads to a dangerous decrease in blood pressure and consequently the person will faint. Histamine also increases permeability of blood vessels leading to the leak of extracellular fluid and subsquent edema. It also causes the diameter of the airways todecrease, and increased mucus secretion(this happens in asthma especially). Epiglottis swelling may suffocate the patient. Increased fluid secretion and peristalsis into the gastrointestinal tractcausing diarrhoea and vomiting. ewww. well. but this horrid horrid thing only happens when u take in a HELL lot of allergens. Usually u'd just get itching/hives. :)
ahaha. and thats it really. if you want to know the immunological basis of your allergies.
as for asthma, it is basically alsocaused by the whole Ige histamine release crap. Mast cell degranulation, leading to the recruitment of neutrophils, eosinophils and basophils which are atrracted by chemokines and other mediateors released by mast cells. Casue tissue destruction. Thickedn walls of bronchus. blah. many other things.
how to fix asthma? bronchodilators, avoid allergens (dust mite feces, pollen etc), steroids to suppress your enthusiastic immune system, mast cell stabilizers to prevent degranulation, leukotriene antagonists and synthesis inhibitors to decrease mucus production and viasodialtion. THeophylline to relax bronchus smooth muscles.
Another crappy thing with immune systems is that your body can sometimes react to self antigens and therefore cause a coupel of these diseases. Type I diabetes mellitus, multiple sclerosis, vitiligo, pernicious anemia, arthritis, systemic lupus erythematosus(very very awful disese btw:p)
HURH. I am TIRED. i need my sleep. paper in slgiuhtly more than 24 hours now. zzz.
-------------------A world Of PeaCe--------------- ; {3:58 AM}
Needs/wants
1. Puppy!
2. Incanto charm
4. Makeup set. I dont really need blushers or glosses. foundation, eyeshadows and brushes. eyelash curlers extremely useful:D
5. la senza/ river island/ topshop/ mango/ forever21/ lovely underwear brands,makeup vouchers
6. Loads of underwear:D
7. an acoustic guitar/portable drumset
8. synthesizer/sampler- one where i can compose and record stuff
9. strawberry/some fruit/hazelnut/mint white/milk chocolate.
10.pasta making machine
12.A pair of 33/34 sized havaianas
16.DARK purple nailpolish
17.cooking lessons
19.loads of accessories
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